Do Your Legs Feel Heavy, Swollen and Sore?
You could be experiencing the first signs of Chronic Venous Insufficiency. Diosmin + Hesperidin (Daflon® 1000) helps reduce and relieve the following signs and symptoms associated with this progressive condition 1
Heavy, Painful or Swollen Legs
Tired Legs
Spider or Varicose veins
Cramping or Leg pain
Looks familiar?
Take our quick self-assessment quiz and use your result to help guide your next steps.
Does Your Bum Itch and Bleed?
You could be experiencing the uncomfortable itching and bleeding caused by Hemorrhoids. Diosmin + Hesperidin (Daflon® 1000) works quickly to reduce and relieve the following signs and symptoms of acute and recurring hemorrhoids 2,3 .
Incomplete evacuation
Bleeding
Itchy bottom
Pain or discomfort
Chronic Venous Insufficiency
Doesn’t have to stop you putting your best foot forward.
Chronic Venous Insufficiency is a progressive condition affecting leg veins and blood circulation. This can lead to blood pooling in the legs, which can be very painful and may even lead to ulcers if left untreated.
Diosmin + Hesperidin (Daflon® 1000) is clinically proven to relieve chronic venous insufficiency symptoms such as leg pain and heaviness. It also protects capillaries and improves microcirculation. Finally, It helps prevent disease progression. 1
Hemorrhoids
Don't need to be an uncomfortable fact of life.
Hemorrhoids, or piles, are swellings inside and around your anus as a result of increased pressure on the blood vessels in your bottom, which causes them to stretch and swell, in a similar way to varicose veins.
Diosmin + Hesperidin (Daflon® 1000) is clinically proven to quickly relieve the symptoms of hemorrhoids and reduce the frequency with which episodes recur. 2,3
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To learn more about living with Chronic Venous Insufficiency and Hemorrhoidal disease and how Diosmin + Hesperidin (Daflon® 1000) could help you manage your symptoms.
Safety Information:
Diosmin + Hesperidin (Daflon® 1000)
COMPOSITION: Micronized, purified flavonoid fraction 1000 mg: 900 mg diosmin; 100 mg flavonoids expressed as hesperidin.
INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks.
DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.
CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients.
WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.
INTERACTION: None.
PREGNANCY/LACTATION: Treatment should be avoided.
UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema.
PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance.
PRESENTATION: Pack of 30 film-coated tablets.
STORAGE: Store at temperatures not exceeding 30°C.
For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph.
SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210.
Further information available upon request.
Diosmin + Hesperidin (Daflon® 500)
COMPOSITION: Micronized, purified flavonoid fraction 500 mg: 450 mg diosmin; 50 mg flavonoids expressed as hesperidin.
INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks.
DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.
CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients.
WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.
INTERACTION: None.
PREGNANCY/LACTATION: Treatment should be avoided.
UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema.
PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance.
PRESENTATION: Pack of 30 film-coated tablets.
STORAGE: Store at temperatures not exceeding 30°C.
For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph.
SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210.
Further information available upon request.
References:
- Adapted from Nicolaides A, Kakkos S, Baekgaard N, et al. Management of chronic venous disorders of the lower limbs. Guidelines according to scientific evidence. Part I. Int Angiol. 2018;37(3):181-254.1
- Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
- Godeberge P. Daflon 500mg is significantly more effective than placebo in the treatment of hemorrhoids. Phlebology. 1992;7(suppl 2):61-63.*
2025