Stop, Relieve and Prevent with Diosmin + Hesperidin (Daflon® 1000)
Diosmin + Hesperidin (Daflon® 1000) is an effective oral treatment for the effective reduction and relief of hemorrhoid symptoms. 1
What are Hemorrhoids?
Hemorrhoids are clusters of swollen veins in your anus and lower rectum, similar to varicose veins.
They are a result of increased pressure on the blood vessels in your bottom and can develop inside the rectum (internal hemorrhoids) or under the skin around the anus (external hemorrhoids), often leading to anal discomfort, bleeding, itching or pain.
What do hemorrhoids look like?
Do you have hemorrhoids ?
The symptoms of hemorrhoids are many and varied. Typically, hemorrhoidal swelling leads to pain and itchiness and you might feel a bulge in your bottom, experience anal discharge, redness and inflammation, or see blood when using the toilet. If you experience this or any of the illustrated symptoms for the first time (or if your symptoms extend beyond a couple of days), you should consult a health care professional to rule out other conditions instead of self-treating right away.
Incomplete evacuation
Bleeding
Itchy bottom
Pain or discomfort
Looks familiar?
Diosmin + Hesperidin (Daflon® 1000) is a medicinal product that treats the underlying cause of hemorrhoids for rapid relief and prevention of recurring symptoms.
Treat Your Symptoms Early
Hemorrhoidal symptoms can start off quite mildly and often resolve on their own, but this isn’t always the case. Understand the benefits of taking action to treat and prevent hemorrhoid symptoms. 2
External Hemorrhoids are what most people think of when they picture hemorrhoids. Location is the only difference between the two different types of piles, but the difference in discomfort can be considerable. External hemorrhoids form on the outside of the anus, directly on the opening where there are lots of nerve endings, so can be particularly itchy and painful.
Internal Hemorrhoids are formed deep inside the anus and are not usually visible. They can resolve without treatment, but occasionally they will swell and protrude from the anus. Prolapsed hemorrhoids are internal hemorrhoids that have grown to the point that they protrude from the anus. Severity of internal hemorrhoids is measured using a grading system, based on how far they protrude:
Grade 1
- Bleeding,
- Visible on proctoscopy,
- Protrusion on straining ,
- No prolapse
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Grade 1
There may be bleeding, discomfort and itching, and protrusion on straining, but no evidence of prolapse. It is nonetheless essential that you treat from this first stage to avoid worsening symptoms.
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Grade 2
- Bleeding,
- Prolapse visible at anal margin during straining,
- Spontaneous return when straining ends
Learn more
Grade 2
Without treatment, your condition may worsen, leading to pain when using the toilet, bleeding and hemorrhoids that tend to prolapse when straining, but reduce when straining ceases.
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Grade 3
- Bleeding,
- Visible on proctoscopy
- Protrusion on straining
- Prolapse requiring manual reduction
Learn more
Grade 3
When hemorrhoids progress to Grade 3, bleeding is more frequent and your piles will prolapse on straining and need to be pushed back in. You can do this yourself. If there is a thrombosis (blood clot inside the vein) as well, the pain may be very strong.
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Grade 4
- Permanent and irreducible prolapse,
- Bleeding,
- Discharge
Learn more
Grade 4
Is the most serious stage. You will have permanent piles that you can’t push back in yourself without pain in addition to previous signs and symptoms. Surgery in addition to venoactive treatments such as Daflon becomes essential.
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The main symptoms of hemorrhoidal disease that can occur at all grades of the disease can be bleeding, pain, itching and discomfort.
RISK FACTORS YOU CAN CONTROL 4
Inactivity
Constipation
Heavy lifting
Toilet habits
RISK FACTORS YOU CAN’T CONTROL 4
Age
Pregnancy
Genetics
What are the risk factors for Hemorrhoidal disease?
Hemorrhoidal disease affect people from all walks of life at various stages in their lives. Main risk factors for hemorrhoidal disease include chronic constipation, obesity, increasing age or pregnancy. But there are many reasons you might find yourself looking for solutions to hemorrhoids, some of which you can take steps to change.
Are You Sitting Comfortably? You Can with Diosmin + Hesperidin (Daflon® 1000)
Daflon is an effective, clinically proven oral medication for the relief of hemorrhoid symptoms. 1
Preventing Hemorrhoids
Overall lifestyle modifications can help prevent the excess pressure that causes hemorrhoids. Try incorporating some of the following advice into your daily routine to help protect against piles and their recurrence. 2
Eat high fibre foods
Try including more high fibre foods in your diet such as fruits, vegetables, brown rice, wholewheat pasta and wholemeal breads. These will keep your stools soft and avoid constipation (which can lead to straining and result in Hemorrhoids).
Exercise
Regular exercise will help relax muscles and increase blood flow for better healing.
Drink plenty of fluids
Drinking plenty of fluids (especially water) will help keep your stools soft and manageable.
Go when you need to
If you wait to pass a bowel movement, it can result in your stool becoming dry and harder to pass.
Try a fibre supplement
A fibre supplement can help ensure you are getting enough fibre in your diet if you struggle to get enough through foods.
Avoid sitting for too long
Sitting for too long, particularly on the toilet can increase the pressure on the veins around your anus making them more susceptible to Hemorrhoids/prolapse.
Don’t strain
Straining on the toilet can put even more unwanted pressure on the blood vessels and aggravate an already sensitive area.
In addition to lifestyle modifications, there are a range of treatments available for easing the symptoms of hemorrhoids, including gels, creams and suppositories.
Frequently Asked Questions
Do I need a prescription for it?
Diosmin + Hesperidin (Daflon® 1000) is an over-the-counter treatment so no need for a prescription. You may find it in the drugstore. You might even be able to order it online depending on your location.
What is it used for?
Diosmin + Hesperidin (Daflon® 1000) is an oral treatment that helps to reduce the signs and symptoms associated with hemorrhoids, such as bleeding, anal discharge, pain, inflammation, itching, redness (erythema), discomfort, sensation of needing to pass stools, and swelling (edema).
How do I take it correctly for hemorrhoids?
If taking Diosmin + Hesperidin (Daflon® 1000), 3 tablets daily for 4 days, then 2 tablets daily for the next 3 days at mealtimes. will provide relief during acute attacks. After this, 1 tablet once a day for two months will help prevent relapse. For use beyond two months, you should consult your doctor. If you cannot find Diosmin + Hesperidin (Daflon® 1000) and will be taking Diosmin + Hesperidin (Daflon® 500), drink 6 tablets daily for 4 days, then 4 tablets daily for the next 3 days at mealtimes. This will also provide relief during acute attacks. After this, 1 tablet twice a day for two months will help prevent relapse. For use beyond two months, you should consult your doctor.
How long should I take it for?
You should continue taking Diosmin + Hesperidin (Daflon® 1000) one tablet once a day (or Diosmin + Hesperidin (Daflon® 500), one tablet twice a day) for two months after an acute episode to help prevent relapse.
I take a lot of medication, can it be taken with other medications?
You should speak with your doctor and discuss whether Diosmin + Hesperidin (Daflon ®1000) is safe to combine with your other medications.
What is Diosmin + Hesperidin (Daflon ®1000) ?
Diosmin + Hesperidin (Daflon® 1000)’s active ingredient is a micronized purified flavonoid fraction (MPFF). It is composed of citrus bioflavonoids, containing 90% diosmin and 10% other flavonoids expressed as hesperidin.
What does micronised mean?
Micronized means that a substance has been broken into very small particles for more effective absorption.
How tolerable is it?
Diosmin + Hesperidin (Daflon ®1000) is well tolerated, and side effects observed in trials were mild. Possible side effects include hypersensitivity/allergy, gastrointestinal discomfort, dizziness, headaches, malaise, and skin reactions.
Safety Information:
Diosmin + Hesperidin (Daflon®) 1000mg Safety Information
COMPOSITION: Micronized, purified flavonoid fraction 1000 mg: 900 mg diosmin; 100 mg flavonoids expressed as hesperidin.
INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks.
DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.
CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients.
WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.
INTERACTION: None.
PREGNANCY/LACTATION: Treatment should be avoided.
UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema.
PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance.
PRESENTATION: Pack of 30 film-coated tablets.
STORAGE: Store at temperatures not exceeding 30°C.
For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph.
SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210.
Further information available upon request.
Diosmin + Hesperidin (Daflon®) 500mg Safety Information
COMPOSITION: Micronized, purified flavonoid fraction 500 mg: 450 mg diosmin; 50 mg flavonoids expressed as hesperidin.
INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks.
DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.
CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients.
WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.
INTERACTION: None.
PREGNANCY/LACTATION: Treatment should be avoided.
UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema.
PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance.
PRESENTATION: Pack of 30 film-coated tablets.
STORAGE: Store at temperatures not exceeding 30°C.
For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph.
SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210.
Further information available upon request.
References:
- Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
- Lohsiriwat V et al. Hemorrhoids: From basic pathophysiology to clinical Management World.
- Journal of Gastroenterology 2012. May 7;18 (17): 2009-2017. Chronic venous and HemORrhoidal diseases evalUation and Scientific research; Godeberge P.J Gastroenerol Hepatol. 2020;35:557-87
- Godeberge, Sheikh, Lohsiriwat, Jalife, Shelygin. Micronized purified flavonoid fraction in the treatment of hemorrhoidal disease. J Comp Eff Res 2021; 10(10):801-813. Misra M. et al.. British Journal of Surgery 2000, 87, 868-872.
2024