Relieve, Reduce and Treat with Diosmin + Hesperidin (Daflon® 1000).

An oral treatment for heavy painful legs, varicose veins and other symptoms of poor leg vein health 1 .

Do Your Legs Feel Heavy, Swollen and Sore?

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You could be experiencing the first signs of Chronic Venous Insufficiency. Diosmin + Hesperidin (Daflon® 1000) helps reduce and relieve the following signs and symptoms associated with this progressive condition 1

feet of a heavy painful swollen leg

Heavy, Painful or Swollen Legs

Tired Legs

Cramping or Leg pain

Spider or Varicose veins

Looks familiar?

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Does Your Bum Itch and Bleed?

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You could be experiencing the uncomfortable itching and bleeding caused by Hemorrhoids. Diosmin + Hesperidin (Daflon® 1000) works quickly to reduce and relieve the following signs and symptoms of acute and recurring hemorrhoids 2,3 .

Incomplete evacuation

Bleeding

Itchy bottom

Pain or discomfort

Safety Information:

Diosmin + Hesperidin (Daflon® 1000)

COMPOSITION: Micronized, purified flavonoid fraction 1000 mg: 900 mg diosmin; 100 mg flavonoids expressed as hesperidin.​

INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks. 

DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.

CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients. 

WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.

INTERACTION: None. ​

PREGNANCY/LACTATION: Treatment should be avoided. 

UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema. 

PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. 

PRESENTATION: Pack of 30 film-coated tablets. 

STORAGE: Store at temperatures not exceeding 30°C.

For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph. 

SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210. ​

Further information available upon request.​

Diosmin + Hesperidin (Daflon® 500)

COMPOSITION: Micronized, purified flavonoid fraction 500 mg: 450 mg diosmin; 50 mg flavonoids expressed as hesperidin. 

INDICATIONS: Treatment of organic and idiopathic chronic venous insufficiency of the lower limbs with the following symptoms: heavy legs; pain; nocturnal cramps. Treatment of hemorrhoids and acute hemorrhoidal attacks. 

DOSAGE AND ADMINISTRATION: In venous disease: 1000 mg daily. In acute hemorrhoidal attacks: 3000 mg per day for the first 4 days, then 2000 mg per day for 3 days. Method of administration: Oral route.

CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the excipients. 

WARNINGS: The administration of this product for the symptomatic treatment of acute hemorrhoids does not preclude treatment for other anal conditions. The treatment must be short-term. If symptoms do not subside promptly, a proctological examination should be performed and the treatment should be reviewed. Excipients: sodium-free.

INTERACTION: None. 

PREGNANCY/LACTATION: Treatment should be avoided. 

UNDESIRABLE EFFECTS: Common: diarrhea, dyspepsia, nausea, vomiting. Uncommon: colitis. Rare: dizziness, headache, malaise, rash, pruritus, urticaria. Frequency not known: abdominal pain, isolated face, lip, eyelid edema. Exceptionally, Quincke’s edema. 

PROPERTIES: Vascular protector and venotonic. Daflon acts on the return vascular system: it reduces venous distensibility and venous stasis; in the microcirculation, it normalizes capillary permeability and reinforces capillary resistance. 

PRESENTATION: Pack of 30 film-coated tablets. 

STORAGE: Store at temperatures not exceeding 30°C.

For suspected adverse drug reaction, report to the FDA at www.fda.gov.ph. 

SERVIER PHILIPPINES, INC. Unit AD, 11th Floor, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, 1210. ​

Further information available upon request.

References:

  1. Adapted from Nicolaides A, Kakkos S, Baekgaard N, et al. Management of chronic venous disorders of the lower limbs. Guidelines according to scientific evidence. Part I. Int Angiol. 2018;37(3):181-254.1
  2. Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
  3. Godeberge P. Daflon 500mg is significantly more effective than placebo in the treatment of hemorrhoids. Phlebology. 1992;7(suppl 2):61-63.*

2024